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Publikacje naukowe
PUBLIKACJE 2013-2022
2022
Śliwińska A., Figat R., Zgadzaj A., Wileńska B., Misicka A., Nałęcz-Jawecki G., Pietrosiuk A., Sykłowska-Baranek K. Polyscias filicifolia (Araliaceae) Hairy Roots with Antigenotoxic and Anti-Photogenotoxic Activity. Molecules, 2022; 27, 186.
Kawka M., Bubko I., Koronkiewicz M., Gruber-Bzura B,, Graikou K., Chinou I., Jeziorek M., Pietrosiuk A. & Sykłowska-Baranek K. Polyurethane Foam Rafts Supported In Vitro Cultures of Rindera graeca Roots for Enhanced Production of Rinderol, Potent Proapoptotic Naphthoquinone Compound. Cells, 2022; 11(6):1-21.
Naliwajski M., Wileńska B., Misicka A., Pietrosiuk A. Sykłowska-Baranek K. HPLC-PDA-ESI-HRMS-Based Profiling of Secondary Metabolites of Rindera graeca Anatomical and Hairy Roots Treated with Drought and Cold Stress. International Journal of Molecular Sciences, 2022; 23(1):1-17.
Sykłowska-Baranek K., Kamińska M., Pączkowski C., Pietrosiuk A., Szakiel A. Metabolic Modifications in Terpenoid and Steroid Pathways Triggered by Methyl Jasmonate in Taxus × media Hairy Roots. Plants, 2022; 11, 1-18.
Sykłowska-Baranek K., Sygitowicz G., Maciejak-Jastrzębska A., Pietrosiuk A., Szakiel A. Application of priming strategy for enhanced paclitaxel bio-synthesis in Taxus x media hairy root cultures. Cells, 2022;
2021
Graikou K., Damianakos H., Ganos C., Sykłowska-Baranek K., Jeziorek M., Pietrosiuk A., Roussakis C., Chinou I. Chemical Profile and Screening of Bioactive Metabolites of Rindera graeca (A. DC.) Bois. & Heldr. (Boraginaceae) In Vitro Cultures. Plants, 2021; 10(834): 1-11.
Śliwińska A., Białek A., Orłowska R., Mańkowski D., Sykłowska-Baranek K., Pietrosiuk A. Comparative Study of the Genetic and Biochemical Variability of Polyscias filicifolia (Araliaceae) Regenerants Obtained by Indirect and Direct Somatic Embryogenesis as a Source of Triterpenes. International Journal of Molecular Sciences, 2021; 22(5752): 1-21.
Figat R., Zgadzaj A., Geschke S., Sieczka P., Pietrosiuk A., Sommer S., Skrzypczak A. Cytotoxicity and antigenotoxicity evaluation of acetylshikonin and shikonin. Drug and Chemical Toxicology, 2021; 44(2): 140-147.
Śliwińska A., Naliwajski M. R., Pietrosiuk A., Sykłowska-Baranek K. In Vitro Response of Polyscias filicifolia (Araliaceae) Shoots to Elicitation with Alarmone–Diadenosine Triphosphate, Methyl Jasmonate, and Salicylic Acid. Cells, 2021; 10(2): 1-17.
Nowak B., Kawka M., Wierzchowski K., Katarzyna Sykłowska-Baranek K., Pilarek M. MTMS-Based Aerogel Constructs for Immobilization of Plant Hairy Roots: Effects on Proliferation of Rindera graeca Biomass and Extracellular Secretion of Naphthoquinones. Funct. Biomater., 2021; 12, 19. https://doi.org/10.3390/jfb12010019
2020
Szypuła W., Wileńska B., Misicka A., Pietrosiuk A. Huperzine A and Huperzine B Production by Prothallus Cultures of Huperzia selago (L.) Bernh. ex Schrank et Mart. Molecules, 2020; (25)14. DOI: 10.3390/molecules25143262.
Figat R., Śliwińska A., Stochmal A., Soluch A., Sobczak M., Zgadzaj A., Sykłowska-Baranek K., Pietrosiuk A. Antigenotoxic, Anti-photogenotoxic, and Antioxidant Properties of Polyscias filicifolia Shoots Cultivated In Vitro. Molecules, 2020; (25)5. DOI: 10.3390/molecules25051090.
2019
Rozdziały w Plant Cell and Tissue Differentiation and Secondary Metabolites: Fundamentals and Applications. Springer, 2019:
Sykłowska-Baranek K., Sygitowicz G., Pietrosiuk A. Development of Taxus spp. hairy root cultures for enhanced taxane production. 2019, 1-19.
Szypuła W.J., Pietrosiuk A. Production of cholinesterase-inhibiting compounds in in vitro cultures of club mosses. 2019, 1-40.
Sykłowska‑Baranek K., Rymaszewski W., Gaweł M., Rokicki P., Pilarek M., Grech-Baran M., Hennig J., Pietrosiuk A. Comparison of elicitor-based effects on metabolic responses of Taxus×media hairy roots in perfluorodecalin supported two-phase culture system. Plant Cell Reports, 2019. DOI: 10.1007_s 00299-018-2351-0.
Jeziorek M., Damianakos H., Kawiak A., Laudy A. E., Zakrzewska K., Sykłowska-Baranek K., Chinou I., Pietrosiuk A. Bioactive rinderol and cynoglosol isolated from Cynoglossum columnae Ten. in vitro root culture. Industrial Crops & Products, 2019; 137:446-452.
2018
Patent uzyskany w 2018 r.
Patent nr PL 227837 B1 na wynalazek pt. "Zastosowanie perfluorozwiązków do ekstrakcji metabolitów roślinnych". Twórcy: K. Sykłowska‑Baranek, M. Pilarek, A. Pietrosiuk. Uprawniony z patentu: Warszawski Uniwersytet Medyczny; Politechnika Warszawska. Data udzielenia patentu: 31.01.2018 WUP 01/18
Sykłowska‑Baranek K., Łysik K., Jeziorek M., Wencel A., Gajcy M., Pietrosiuk A. Lignan accumulation in two-phase cultures of Taxus x media hairy roots. Plant Cell, Tissue and Organ Culture, 2018, doi.org/10.1007/s11240-018-1390-0
Śliwińska A., Sykłowska-Baranek K., Kośmider A., Granica S., Miszczak K., Nowicka G., Kasztelan A. Podsadni P., Turło J., Pietrosiuk A. Stimulation of phenolic compounds production in the in vitro cultivated Polyscias filicifolia Bailey shoots and evaluation of the antioxidant and cytotoxic potential of plant extracts. Acta Societatis Botanicorum Poloniae, 2018, doi: 10.5586/asbp.3586
Sykłowska‑Baranek K., Szala K., Pilarek M., Orzechowski R., Pietrosiuk A. A cellulase-supported two-phase in situ system for enhanced biosynthesis of paclitaxel in Taxus × media hairy roots. Acta Physiologiae Plantarum, 2018, doi: 10.1007/s11738-018-2777-6
Figat R, Zgadzaj A., Geschke S., Sieczka P., Pietrosiuk A., Sommer S., A. Skrzypczak A. Cytotoxicity and antigenotoxicity evaluation of acetylshikonin and shikonin. Drug and Chemical Toxicology, 2018, doi:10.1080/01480545.2018.1536710
2017
Jeziorek M., Sykłowska-Baranek K., Pietrosiuk A. Hairy root cultures for the production of anti-cancer naphthoquinone compounds. Current Medicinal Chemistry, 2017; 24: 1-22. DOI: 10.2174/0929867324666170821161844.J
2016
Damianakos H., Jeziorek M., Sykłowska-Baranek K., Buchwald W., Pietrosiuk A., Chinou I. Pyrrolizidine alkaloids from Cynoglossum columnae Ten. (Boraginaceae), Phytochemistry Letters, 2016; 15: 234-237. DOI:10.1016/j.phytol.2016.02.005.
Lenkiewicz A.M,. Czapski G.A., Jęsko H., Wilkaniec A., Szypuła W., Pietrosiuk A., Uszyńska A.M., Adamczyk A. Potent effects of alkaloid-rich extract from Huperzia selago against sodium nitroprusside-evoked PC12 cells damage via attenuation of oxidative stress and apoptosis. Folia Neuropathologica, 2016; 54: 156-166. DOI:10.5114/fn.2016.60361
2015
Mistrzak P., Celejewska-Marciniak H., Szypuła W.J., Olszowska O., Kiss A.K. Identification and quantitative determination of pinoresinol in Taxus x media Rehder needles, cell suspension and shoot cultures Acta Societatis Botanicorum Poloniae 2015, 84, 125-132. DOI 10.5586/asbp.2014.038
Grech-Baran M., Sykłowska-Baranek K., Pietrosiuk A. Approaches of Rhodiola kirilowii and Rhodiola rosea field cultivation in Poland and their potential health benefits. Annals of Agricultural and Environmental Medicine 2015,Vol 22, No 2, 281–285
K.Sykłowska-Baranek, M.Pilarek, M.Bonfil, K.Kafel, A.Pietrosiuk. Perfluorodecalin-supported system enhances taxane production in hairy root cultures of Taxus x media var. Hicksii carrying a taxadiene synthase transgene. Plant Cell Tiss Organ Cult (2015) 120:1051–1059 .DOI 10.1007/s11240- 014-0659-1
K.Sykłowska-Baranek, M. Grech-Baran, M.R. Naliwajski, M. Bomfill, A. Pietrosiuk Paclitaxel production and PAL activity in hairy root cultures of Taxus x media var. Hicksii carrying a taxadiene synthase transgene elicited with nitric oxide and methyl jasmonate. Acta Physiologiae Plantarum 2015 DOI: 10.1007/s11738-015-1949-x
A. Skrzypczak, N. Przystupa, A. Zgadzaj, A. Parzonko, K.Sykłowska-Baranek, K. Paradowska, G. Nałęcz-Jawecki, Antigenotoxic,anti-photogenotoxic and antioxidant activities of natural naphtoquinone shikonin and acetylshikonin and Arnebia euchroma callus extracts evaluted by the umu-test and EPR method.Toxicology in Vitro 2015 DOI:10.1016/j.tiv.2015.09.029.
Czapski G., Szypula W. J., Kudlik M., Wileńska B., Kania M.; Danikiewicz W., Adamczyk A. Assessment of antioxidative activity of alkaloids from Huperzia selago and Diphasiastrum complanatum using in vitro systems. Folia Neuropathol 2014, 52, 394-406. DOI 10.5114/fn.2014.47840.
Sykłowska-Baranek K., Pilarek M., Cichosz M., Pietrosiuk A. Liquid Perfluorodecalin Application for In Situ Extraction and Enhanced Naphthoquinones Production in Arnebia euchroma Cell Suspension Cultures.Appl Biochem Biotechnol (2014), 172:2618–2627, DOI 10.1007/s12010-013-0701-5.
Grech-Baran M., Sykłowska-Baranek K., Krajewska-Patan A., Wyrwał A., Pietrosiuk A., (2013) Biotransformation ofcinnamyl alcohol to rosavins by non-transformed wild type and hairy root cultures of Rhodiola kirilowii. Biol Let.DOI:101007/s10529-013-1401-5
Grech-Baran M., Sykłowska-Baranek K., Pietrosiuk A., (2014) Biotechnological approaches to enhance salidroside, rosin and its derivatives production in selected Rhodiola spp.in vitro cultures. DOI 10.1007/s11101-014-9368-y
Urbańska, N.; Giebułtowicz, J.; Olszowska, O.; Szypuła, W. J. 2014. The growth and saponin production of Platycodon grandiflorum (Jacq.) A. DC. (Chinese bellflower) hairy roots cultures maintained in shake flasks and mistbioreactor. Acta Societatis Botanicorum Poloniae 83(3):229–237 DOI: 10.5586/asbp.2014.017
Damianakos H., Jeziorek M., Pietrosiuk A.,Chinou I. The Chemical Profile of Pyrrolizidine Alkaloids from Selected Greek Endemic Boraginaceae Plants Determined by Gas Chromatography/Mass Spectrometry.1244 Damianakos et al.: Journal of AOAC International Vol. 97, No. 5, 2014
2013
Sykłowska-Baranek K., Pilarek M., Pietrosiuk A. (2013). Zgłoszenie patentowe nr P.404726 (2013–07-16) „Zastosowanie perfluorozwiązków do ekstrakcji metabolitów roślinnych”
Szypuła W. (2013). O filogenezie i systematyce rodziny widłakowatych Lycopodiaceae sensu lato - przegląd piśmiennictwa. Acta Botanica Silesiaca, 9: 25-56.
Grech-Baran M., Sykłowska-Baranek K., Giebułtowicz P., Wroczyński P., Pietrosiuk A. (2013). Tyrosol-glycosyltransferase activity and production of salidroside in natural and transformend root cultures of Rhodiola kirilowii (Regel) Regel et Maximowicz. Acta Biol Cracov Bot 55/2
Grech-Baran M., Pietrosiuk A. (2012). Artemisia species in vitro cultures for production of' biologically active secondary metabolites. Biotechnologia. Journal of Biotechnology, Computational Biology and Bionanotechnology, 93(4): 371-380.
Szypula, W. J.; Mistrzak, P.; Olszowska, O. 2013. A new and fast method to obtain in vitro cultures of Huperzia selago (Huperziaceae) sporophytes, a club moss which is a source of huperzine A. Acta Societatis Botanicorum Poloniae, 82(4):313-320.